Akın Fırat Kocaay1, Süleyman Utku Çelik1, Ömer Arda Çetinkaya1, Mehmet Ali Koç2, Seher Demirer1

1Ankara Üniversitesi Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Ankara
2Etimesgut Devlet Hastanesi, Genel Cerrahi Kliniği, Ankara

Keywords: Adrenal glands, management, pheochromocytoma, perioperative care

Abstract

Pheochromocytoma is a rare, benign and catecholaminesecreting tumor that arises from chromaffin tissue within adrenal medulla. Patients with pheochromocytoma may develop serious and potentially fatal cardiovascular and other complications due to the effects of secreted catecholamines, especially in the setting of diagnostic or interventional procedures. The physician should be aware of the clinical manifestations and complications of the excess secretion of hormones and be able to provide proper preoperative management to minimize catecholamine-related pre-, intra-, and postoperative cardiovascular instability and adverse events. So, the perioperative management of pheochromocytoma requires good clinical knowledge on the pathophysiology and potential complications; and depends on adequate preoperative preparation, meticulous intraoperative management and intensive postoperative care. A close communication and coordination between the endocrine surgeon, endocrinologist, cardiologist, and anesthesiologist is crucial and essential pre-requisite for a successful outcome. In this review, we discuss the perioperative approach of the pheochromocytoma and future directions in the management of this disease.