Current Treatment Options in Graves Disease
Orcun Yalav, Orhan Demircan, Gurhan Sakman
Genel Cerrahi AD, Çukurova Üniversitesi Tıp Fakültesi
Keywords: Graves disease, surgical treatment, manangement of graves
Graves disease, the most common cause of hyperthyroidism, is an autoimmune and systemic disease characterized by diffusing goiter, thyrotoxicosis, ophtalmopathy and dermopathy. The treatment alternatives for Graves disease are anti-thyroid drugs, radioiodine therapy and surgery. The primary goal of the treatment is to limit hyperthyroidism and take the symptoms under control rapidly with minimum morbidity and mortality. However no ideal treatment alternative dealing with all of the the above mentioned options has been described yet. Graves ophtalmopathy is the main reason for morbidity and the decrease in quality of life. Total thyroid ablation or glucocorticoid medication is recommended for the patients with Graves ophtalmopathy, whereas, in the abscence of ophtalmopathy, no treatment option is standardized. The treatment of Graves disease should be planned by a multidisciplinary approcah including general surgeons, endocrinologists, nuclear medicine specialists and ophtalmologists. The application of anti-thyroid medications should be the first step of the treatment plan and radioiodine therapy and surgery should be selected according to the charasteristics of the patient.