Primary thyroid lymphoma: case report
Kazım Çağlar Özçelik1, A. Hakan Demirel1, E. Yeşim Atak2
1Yıldırım Beyazıt Üniversitesi, Yenimahalle Eğitim ve Araştırma Hastanesi, Genel Cerrahi Kliniği, Ankara
2Yıldırım Beyazıt Üniversitesi, Yenimahalle Eğitim ve Araştırma Hastanesi, Patoloji Kliniği, Ankara
Keywords: Lymphoma, primary, thyroid
Primary thyroid lymphoma is a rare disease of thyroid gland and constitutes less than 1% of thyroid malignancies. The clinical presentation of it is usually painless, fastgrowing mass in the neck. Usually it is diagnosed by the result of surgery done for a fast growing, rigid and fixed masses with suspected carcinoma. In our case, 71 years old female patient followed in other centers due to multinodular goiter was admitted with fast-growing painless mass in the neck and shortness of breath for last 2 months. Chronic lymphocytic thyroiditis was detected in the patient by preoperative fine needle aspiration biopsy and bilateral total thyroidectomy surgery was underwent due to the rapid growth of the lesion. Specimen pathology of the patient was detected as extranodal primary thyroid lymphoma with aggressive B-cell and mediastinal lymph nodes with metastasis was reported by the postoperative tests performed for staging. Patient was accepted with stage 3 and cyclophosphamide, doxorubicin, vincristine, prednisolone protocol (CHOP) and rituximab chemotherapy was started. While after appropriate treatment the survival of patients varies according to the stage of the disease in the primary thyroid lymphoma, outcome in patients with early stage is good. Recommended treatment is total thyroidectomy in the localized disease and chemotherapy, radiotherapy or combinations in advanced stages.