A rare cause of elevated thyroglobulin level in papillary thyroid cancer: residual thyroid tissue in thyroglossal canal cyst
Semra Aytürk1, Mehmet Çelik1, Atakan Sezer2, Nuray Can3, Ebru Taştekin3, Ahmet Küçükarda4, Ali Gökyer4, Funda Üstün5,Sibel Güldiken1, Ayşe Armağan Tuğrul1
1Trakya Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Endokrinoloji ve Metabolizma Hastalıkları Bilim Dalı, Edirne
2Trakya Üniversitesi Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Edirne
3Trakya Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Edirne
4Trakya Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Edirne
5Trakya Üniversitesi Tıp Fakültesi, Nükleer Tıp Anabilim Dalı, Edirne
Keywords: Ectopic thyroid tissue, thyroglossal ductus cyst, thyroid carcinoma
Abstract
Well differentiated thyroid cancers comprise 90% of all primary thyroid cancers. Patients must be evaluated every 6 months with neck ultrasonography, thyroid stimulating hormone (TSH), thyroglobulin (Tg) and anti-thyroglobulin (anti-Tg) level measurements. During follow-up, detection of persistent Tg level increase despite anti-Tg negativity may be due to recurrence, residue or metastasis of differentiated thyroid cancer. In rare instances, ectopic thyroid tissue may be present. We aimed to present a papillary thyroid carcinoma case who was diagnosed with ectopic thyroid tissue in thyroglossal canal cyst (TCC) by imaging modalities after detection of increased Tg level following total thyroidectomy.