Alpen Yahya Gümüşoğlu1, Ahmet Cem Dural1, Cevher Akarsu1, Savaş Tuna2, Mehmet Karabulut1, Burak Kankaya1, Nurten Sever3, Muhammet Ferhat Çelik4, Halil Alış1

1Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Genel Cerrahi Kliniği, İstanbul
2Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Onkoloji Kliniği, İstanbul
3Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Patoloji Kliniği, İstanbul
4Yedikule Surp Pırgiç Ermeni Hastanesi, Genel Cerrahi Kliniği, İstanbul

Keywords: Colorectal invasive micropapillar carcinoma, papillary thyroid cancer, synchronous second primary cancer


The second primary malignancies are rarely detected in colorectal cancers and often diagnosed during the oncological follow-up. In recent years, the increased use of positron emission tomography (PET-CT) during the oncological follow-up has led to an increase in the number of thyroid incidentalomas detected. The literature shows that there are second primaries of various organs in colorectal cancer. In colonic adenocarcinoma, the invasive micropapillary carcinoma (IMPC) variant was first described in 2005. However, the detection of synchronous papillary thyroid carcinoma in a patient diagnosed with IMPC in colorectal system is not previously encountered in literature. Therefore, we aimed to share a 59-year-old case with a history of sigmoid colon cancer with histopathologic diagnosis of invasive micropapillar adenocarcinoma in whom metastatic multifocal papillary thyroid cancer was detected in PET-CT imaging performed due to non-regressive carcinoembryonic antigen level during his oncological follow-up.